Job Details

Overview

The CDI Tycko Lab has a long standing research program on epigenetics and DNA methylation in normal human development and in common diseases, including cancer, Down syndrome, Alzheimer’s disease and other neurodegenerative disorders, and autoimmune diseases.  Areas of current emphasis include mechanistic studies on genetic-epigenetic interactions that occur in cis and in trans, using both human samples and mouse models, and the use of epigenomic mapping as a “post-GWAS” method to identify genes and DNA variants that underlie disease susceptibility. We are also studying epigenetically-acting anti-cancer drugs, seeking to understand how these agents affect tumor cells and stromal and immune system cells in the tumor microenvironment. Opportunities for post-doctoral training in our group therefore encompass the areas of genome and epigenome analysis using whole genome and targeted approaches in human samples and informative mouse models, the development of useful bioinformatic methods, and pre-clinical studies of epigenetically-acting anti-cancer therapies and their effects on the tumor microenvironment in tumor-prone mouse models.

The Center for Discovery and Innovation (CDI), was established by Hackensack Meridian Health (HMH)as an academic basic and translational research enterprise to rapidly translate science innovation to the clinic to improve outcomes for patients with cancer, infectious diseases, autoimmune disease and other acute and chronic diseases.  The CDI has grown rapidly since its origins in 2019, and now has 27 labs, 150 scientists and support personnel, who are supported by more than 85 grants and contracts. Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, and pharmacology.

Responsibilities

A day in the life of a Postdoctoral Research Fellow- Genetics/ Epigenetics, CDI at Hackensack Meridian Health includes:

• Conducts research and/or laboratory tasks and experiments under direct supervision.
• Collects, analyzes and interprets data.
• Creates reports from analysis of initial observations and conclusions.
• Presents findings to higher level staff.
• Presents results in internal and external research forums such as scientific conferences, lab meetings and institutional seminars.
• Handles moderately complex issues and problems and refers more complex issues to higher-level staff.
• Participates in grant and manuscript writing, as appropriate.
• Other duties and/or projects as assigned.
• Adheres to HMH Organizational competencies and standards of behavior.

Qualifications

Education, Knowledge, Skills and Abilities Required:

• A Ph.D. degree in scientific discipline.
• Minimum publication or in preparation of two articles as first author in a reputable peer-reviewed scientific journal.
• Excellent written and verbal skills
• Good problem solving skills.
• Ability to conduct independent research.
• Ability to work effectively in a team.
• Technical laboratory experiment techniques. Examples include but are not limited to RT-PCR, RNA/DNA extraction/preparation, staining, sample embedding, sectioning, etc.
• Proficient computer skills including but not limited to Microsoft Office and Google Suite platforms.

Education, Knowledge, Skills and Abilities Preferred:

• Experience working in a BSL2/BSL3 lab facility.

Licenses and Certifications Required:

• Lab specific.

Licenses and Certifications Preferred:

• Lab specific.

If you feel that the above description speaks directly to your strengths and capabilities, then please apply today!      

Our Network

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